Use of Bifunctional Immunotherapeutic Agents to Target Breast Cancer

Award Number : W 81 XWH - 04 - 1 - 0466 TITLE : Use of Bifunctional Immunotherapeutic Agents To Target Breast Cancer

Calculation of absorbed dose rate in the lungs, ribs and skin by the mammosite applicator in breast cancer brachytherapy with MCNP

Introduction: Breast cancer is the most common cancer among women. Brachytherapy is one of the ways to treat breast cancer. In brachytherapy treatments, high-dose sources are used in interstitial placement. Here, Iridium-192 is used. This source emits gamma rays with energies ranging from 136 kV to 1060 kV electron volts. The activity of the used spring is 10 Ci. The simulated ...

Design, synthesis and biological evaluation of Ciprofloxacin- peptide conjugates as anticancer agents

Cancer has emerged as a leading cause of death throughout the world. Peptides are a novel class of anticancer agents that can specifically target cancer cells with low toxicity to normal tissues and thus, offer new opportunities for future cancer treatment. On the other hand, Ciprofloxacin, an antibiotic, also known to its anticancer property for enabling cell cycle arrest and creating double s...

Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15

Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently under intensive investigation in preclinical and clinical trials. Cancer vaccines induce pe...

Design, synthesis and biological evaluation of Ciprofloxacin- peptide conjugates as anticancer agents

Cancer has emerged as a leading cause of death throughout the world. Peptides are a novel class of anticancer agents that can specifically target cancer cells with low toxicity to normal tissues and thus, offer new opportunities for future cancer treatment. On the other hand, Ciprofloxacin, an antibiotic, also known to its anticancer property for enabling cell cycle arrest and creating double s...